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Santa Ana, CA - 25 Best Alcohol & Drug Rehab Centers

This guide to the best rehab facilities in Santa Ana for 2026 helps you explore treatment options for drug and alcohol addiction and connect with professional care near you.

Santa Ana Treatment Centers

Cornerstone Adult OutpatientFeatured Image

Cornerstone Adult Outpatient

Location Pin Icon 1950 East 17th Street / Suite 150, Santa Ana, CA 92705

Phone Icon 714-547-4300

Phone Icon 714-730-5399

URL address dropdown icon
http://www.CornerstoneSoCal.com

heartbeat IconOperating Model

  • Private for-profit organization

heartbeat IconFacility Credentials & Oversight

  • State Substance use treatment agency
  • State department of health
  • The Joint Commission

heartbeat IconAges Served

  • Young Adults
  • Adults
John Henry FoundationFeatured Image

John Henry Foundation

Location Pin Icon 403 North Susan Street, Santa Ana, CA 92703

Phone Icon 714-480-0025

Phone Icon 714-480-0025 x202

URL address dropdown icon
http://www.johnhenry.org

heartbeat IconTreatment Center Type

  • Residential treatment center (RTC) for adults

heartbeat IconOperating Model

  • Private non-profit organization

heartbeat IconAges Served

  • Young Adults
  • Adults
Newport AcademyFeatured Image

Newport Academy

Location Pin Icon 9951 Highcliff Drive, Santa Ana, CA 92705

Phone Icon 877-820-6371

URL address dropdown icon
http://www.newportacademy.com

heartbeat IconOperating Model

  • Private for-profit organization

heartbeat IconFacility Credentials & Oversight

  • State department of health
  • The Joint Commission

heartbeat IconAges Served

  • Children/Adolescents
  • Young Adults
  • Adults
Newport InstituteFeatured Image

Newport Institute

Location Pin Icon 12822 Periwinkle Drive, Santa Ana, CA 92705

Phone Icon 855-272-7451

URL address dropdown icon
http://www.newportinstitute.com

heartbeat IconTreatment Center Type

  • Residential treatment center (RTC) for adults

heartbeat IconOperating Model

  • Private for-profit organization

heartbeat IconAges Served

  • Young Adults
  • Adults
Orange County Healthcare AgencyFeatured Image

Orange County Healthcare Agency

Location Pin Icon 200 West Santa Ana Boulevard / Suites 100 and 175, Santa Ana, CA 92701

Phone Icon 714-834-3840

Phone Icon 714-480-6660

URL address dropdown icon
http://ochealthinfo.com

heartbeat IconOperating Model

  • Local, county, or community government

heartbeat IconFacility Credentials & Oversight

  • State Substance use treatment agency
  • State department of health

heartbeat IconAges Served

  • Young Adults
  • Adults
Cooper Fellowship IncFeatured Image

Cooper Fellowship Inc

Location Pin Icon 409 North Cooper Street, Santa Ana, CA 92703

Phone Icon 714-554-1152

URL address dropdown icon
http://www.cooperfellowship.com

heartbeat IconOperating Model

  • Private non-profit organization

heartbeat IconFacility Credentials & Oversight

  • State Substance use treatment agency

heartbeat IconAges Served

  • Young Adults
  • Adults

100% Confidential and free

Orange County Healthcare AgencyFeatured Image

Orange County Healthcare Agency

Location Pin Icon 401 West Civic Center Drive / Suite 500, Santa Ana, CA 92701

Phone Icon 714-480-6650

URL address dropdown icon
http://www.ochealthinfo.com

heartbeat IconOperating Model

  • Local, county, or community government

heartbeat IconFacility Credentials & Oversight

  • State Substance use treatment agency

heartbeat IconAges Served

  • Young Adults
  • Adults
Santa Ana Comprehensive TreatmentFeatured Image

Santa Ana Comprehensive Treatment

Location Pin Icon 2101 East 1st Street, Santa Ana, CA 92705

Phone Icon 714-581-9181

Phone Icon 714-542-3581

URL address dropdown icon
http://www.ctcprograms.com/location/santa-ana-comprehensive-treatment-center/

heartbeat IconOperating Model

  • Private for-profit organization

heartbeat IconFacility Credentials & Oversight

  • State Substance use treatment agency
  • State department of health
  • Commission on Accreditation of Rehabilitation Facilities (CARF)
  • SAMHSA certification for opioid treatment program (OTP)
  • Drug Enforcement Agency (DEA)

heartbeat IconAges Served

  • Young Adults
  • Adults
County of Orange Healthcare AgencyFeatured Image

County of Orange Healthcare Agency

Location Pin Icon 401 West Civic Center Drive / Suite 800, Santa Ana, CA 92701

Phone Icon 714-480-6767

URL address dropdown icon
http://www.ochealthinfo.com

heartbeat IconTreatment Center Type

  • Outpatient mental health facility

heartbeat IconOperating Model

  • Local, county, or community government

heartbeat IconFacility Credentials & Oversight

  • Federally Qualified Health Center

heartbeat IconAges Served

  • Young Adults
  • Adults
  • Seniors
Child Guidance Center IncFeatured Image

Child Guidance Center Inc

Location Pin Icon 600 West Santa Ana Boulevard / Suite 600, Santa Ana, CA 92701

Phone Icon 714-953-4455

Phone Icon 714-953-4455 x629

URL address dropdown icon
http://www.childguidancecenteroc.org

heartbeat IconTreatment Center Type

  • Outpatient mental health facility

heartbeat IconOperating Model

  • Private non-profit organization

heartbeat IconAges Served

  • Children/Adolescents
  • Young Adults
Sensible CareFeatured Image

Sensible Care

Location Pin Icon 2677 North Main Street / Suite 110, Santa Ana, CA 92705

Phone Icon 714-274-7577

URL address dropdown icon
http://www.sensiblecare.com

heartbeat IconTreatment Center Type

  • Outpatient mental health facility

heartbeat IconOperating Model

  • Private for-profit organization

heartbeat IconAges Served

  • Children/Adolescents
  • Young Adults
  • Adults
  • Seniors
Norooz Clinic FoundationFeatured Image

Norooz Clinic Foundation

Location Pin Icon 1560 Brookhollow Drive / Suite 214, Santa Ana, CA 92705

Phone Icon 714-386-9171

URL address dropdown icon
http://www.noroozclinic.com

heartbeat IconTreatment Center Type

  • Community mental health center

heartbeat IconOperating Model

  • Private non-profit organization

heartbeat IconAges Served

  • Children/Adolescents
  • Young Adults
  • Adults
  • Seniors

100% Confidential and free

Nsight Residential Mental HealthFeatured Image

Nsight Residential Mental Health

Location Pin Icon 206 West Sierra Drive, Santa Ana, CA 92707

Phone Icon 949-629-3730

URL address dropdown icon
http://www.nsightrecovery.com

heartbeat IconOperating Model

  • Private for-profit organization

heartbeat IconAges Served

  • Young Adults
  • Adults
  • Seniors
Straight Talk Clinics IncFeatured Image

Straight Talk Clinics Inc

Location Pin Icon 1225 West 6th Street, Santa Ana, CA 92703

Phone Icon 714-972-1402

Phone Icon 714-619-2516

URL address dropdown icon
http://www.StraightTalkCounseling.org

heartbeat IconOperating Model

  • Private non-profit organization

heartbeat IconFacility Credentials & Oversight

  • State Substance use treatment agency
  • State department of health

heartbeat IconAges Served

  • Young Adults
  • Adults
  • Seniors
Neurish WellnessFeatured Image

Neurish Wellness

Location Pin Icon 11621 Las Luces, Santa Ana, CA 92705

Phone Icon 866-525-5197

URL address dropdown icon
http://www.neurishwellness.com

heartbeat IconTreatment Center Type

  • Residential treatment center (RTC) for adults

heartbeat IconOperating Model

  • Private for-profit organization

heartbeat IconAges Served

  • Young Adults
  • Adults
Phoenix HouseFeatured Image

Phoenix House

Location Pin Icon 1207 East Fruit Street, Santa Ana, CA 92701

Phone Icon 714-953-9373

URL address dropdown icon
http://www.phoenixhouseca.org

heartbeat IconOperating Model

  • Private non-profit organization

heartbeat IconFacility Credentials & Oversight

  • State Substance use treatment agency
  • State department of health
  • Commission on Accreditation of Rehabilitation Facilities (CARF)
  • Council on Accreditation (COA)
  • The Joint Commission
  • National Committee for Quality Assurance (NCQA)
  • Federally Qualified Health Center

heartbeat IconAges Served

  • Young Adults
  • Adults
Newport InstituteFeatured Image

Newport Institute

Location Pin Icon 12822 Periwinkle Drive, Santa Ana, CA 92705

Phone Icon 855-272-7451

URL address dropdown icon
http://www.newportinstitute.com

heartbeat IconOperating Model

  • Private for-profit organization

heartbeat IconFacility Credentials & Oversight

  • State department of health
  • The Joint Commission

heartbeat IconAges Served

  • Young Adults
  • Adults
Newport AcademyFeatured Image

Newport Academy

Location Pin Icon 9951 Highcliff Drive, Santa Ana, CA 92705

Phone Icon 877-820-6371

URL address dropdown icon
http://www.newportacademy.com

heartbeat IconTreatment Center Type

  • Residential treatment center (RTC) for children

heartbeat IconOperating Model

  • Private for-profit organization

heartbeat IconAges Served

  • Children/Adolescents

100% Confidential and free

Newport InstituteFeatured Image

Newport Institute

Location Pin Icon 9881 Deerhaven Drive, Santa Ana, CA 92705

Phone Icon 855-272-7451

URL address dropdown icon
http://www.newportinstitute.com

heartbeat IconTreatment Center Type

  • Residential treatment center (RTC) for adults

heartbeat IconOperating Model

  • Private for-profit organization

heartbeat IconAges Served

  • Young Adults
  • Adults
Newport InstituteFeatured Image

Newport Institute

Location Pin Icon 9881 Deerhaven Drive, Santa Ana, CA 92705

Phone Icon 855-272-7451

URL address dropdown icon
http://www.newportinstitute.com

heartbeat IconOperating Model

  • Private for-profit organization

heartbeat IconFacility Credentials & Oversight

  • State department of health
  • The Joint Commission

heartbeat IconAges Served

  • Young Adults
  • Adults
Newport InstituteFeatured Image

Newport Institute

Location Pin Icon 10022 Miramar Circle, Santa Ana, CA 92705

Phone Icon 855-272-7451

URL address dropdown icon
http://www.newportinstitute.com

heartbeat IconTreatment Center Type

  • Residential treatment center (RTC) for adults

heartbeat IconOperating Model

  • Private for-profit organization

heartbeat IconAges Served

  • Young Adults
  • Adults
Newport InstituteFeatured Image

Newport Institute

Location Pin Icon 10022 Miramar Circle, Santa Ana, CA 92705

Phone Icon 855-272-7451

URL address dropdown icon
http://www.newportinstitute.com

heartbeat IconOperating Model

  • Private for-profit organization

heartbeat IconFacility Credentials & Oversight

  • State department of health
  • The Joint Commission

heartbeat IconAges Served

  • Young Adults
  • Adults
DAmore HealthcareFeatured Image

DAmore Healthcare

Location Pin Icon 2534 South Deegan Drive, Santa Ana, CA 92704

Phone Icon 714-375-1110

URL address dropdown icon
http://www.damorementalhealth.com

heartbeat IconTreatment Center Type

  • Residential treatment center (RTC) for adults

heartbeat IconOperating Model

  • Private for-profit organization

heartbeat IconAges Served

  • Young Adults
  • Adults
  • Seniors
PES/EBS IncFeatured Image

PES/EBS Inc

Location Pin Icon 600 West Santa Ana Boulevard / Suite 108, Santa Ana, CA 92701

Phone Icon 530-888-1010

URL address dropdown icon
http://www.pesprograms.com

heartbeat IconOperating Model

  • Private for-profit organization

heartbeat IconFacility Credentials & Oversight

  • State Substance use treatment agency

heartbeat IconAges Served

  • Young Adults
  • Adults

100% Confidential and free

Axis Mental HealthFeatured Image

Axis Mental Health

Location Pin Icon 1604 West Santa Ana Boulevard, Santa Ana, CA 92703

Phone Icon 855-944-2533

URL address dropdown icon
http://www.axismentalhealth.com

heartbeat IconTreatment Center Type

  • Residential treatment center (RTC) for adults

heartbeat IconOperating Model

  • Private for-profit organization

heartbeat IconAges Served

  • Adults

100% Confidential and free