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Greenville, SC - 9 Best Alcohol & Drug Rehab Centers

This guide to the best rehab facilities in Greenville for 2026 helps you explore treatment options for drug and alcohol addiction and connect with professional care near you.

Greenville Treatment Centers

Miracle HillFeatured Image

Miracle Hill

Location Pin Icon 1916 North Pleasantburg Drive, Greenville, SC 29609

Phone Icon 864-631-0088

URL address dropdown icon
http://www.miraclehill.org/

heartbeat IconOperating Model

  • Private non-profit organization

heartbeat IconAges Served

  • Young Adults
  • Adults
  • Seniors
Life Line Services LLCFeatured Image

Life Line Services LLC

Location Pin Icon 16 Mills Avenue / Suite 8, Greenville, SC 29605

Phone Icon 864-775-5509

URL address dropdown icon
http://chooselifeline.com

heartbeat IconOperating Model

  • Private for-profit organization

heartbeat IconFacility Credentials & Oversight

  • SAMHSA certification for opioid treatment program (OTP)
  • Drug Enforcement Agency (DEA)

heartbeat IconAges Served

  • Young Adults
  • Adults
Greater Greenville Mental HealthFeatured Image

Greater Greenville Mental Health

Location Pin Icon 124 Mallard Street, Greenville, SC 29601

Phone Icon 864-241-1040

URL address dropdown icon
http://www.greatergreenvillemhc.com

heartbeat IconTreatment Center Type

  • Community mental health center

heartbeat IconOperating Model

  • State government

heartbeat IconAges Served

  • Children/Adolescents
  • Young Adults
  • Adults
  • Seniors
Phoenix CenterFeatured Image

Phoenix Center

Location Pin Icon 130 Industrial Drive / Suite 130, Greenville, SC 29607

Phone Icon 864-467-3770

URL address dropdown icon
http://www.phoenixcenter.org

heartbeat IconOperating Model

  • State government

heartbeat IconFacility Credentials & Oversight

  • State Substance use treatment agency
  • State department of health
  • Commission on Accreditation of Rehabilitation Facilities (CARF)

heartbeat IconAges Served

  • Young Adults
  • Adults
Greenville Metro Treatment CenterFeatured Image

Greenville Metro Treatment Center

Location Pin Icon 602 Airport Road / Suite C, Greenville, SC 29607

Phone Icon 864-234-7952 x15505

URL address dropdown icon
http://www.newseason.com/

heartbeat IconOperating Model

  • Private for-profit organization

heartbeat IconFacility Credentials & Oversight

  • State Substance use treatment agency
  • State department of health
  • Commission on Accreditation of Rehabilitation Facilities (CARF)
  • SAMHSA certification for opioid treatment program (OTP)
  • Drug Enforcement Agency (DEA)

heartbeat IconAges Served

  • Young Adults
  • Adults
Phoenix CenterFeatured Image

Phoenix Center

Location Pin Icon 1400 Cleveland Street, Greenville, SC 29607

Phone Icon 864-467-3790

URL address dropdown icon
http://www.phoenixcenter.org

heartbeat IconOperating Model

  • State government

heartbeat IconFacility Credentials & Oversight

  • State Substance use treatment agency
  • State department of health
  • Commission on Accreditation of Rehabilitation Facilities (CARF)

heartbeat IconAges Served

  • Children/Adolescents
  • Adults

100% Confidential and free

Phoenix CenterFeatured Image

Phoenix Center

Location Pin Icon 6 Dunean Street, Greenville, SC 29602

Phone Icon 864-467-3881

URL address dropdown icon
http://www.phoenixcenter.org

heartbeat IconOperating Model

  • State government

heartbeat IconFacility Credentials & Oversight

  • State Substance use treatment agency
  • State department of health
  • Commission on Accreditation of Rehabilitation Facilities (CARF)

heartbeat IconAges Served

  • Young Adults
  • Adults
  • Seniors
Crossroads Treatment CentersFeatured Image

Crossroads Treatment Centers

Location Pin Icon 157 Brozzini Court / Suite C, Greenville, SC 29615

Phone Icon 864-288-7636

URL address dropdown icon
http://www.crossroadstreatmentcenters.com

heartbeat IconOperating Model

  • Private for-profit organization

heartbeat IconFacility Credentials & Oversight

  • State Substance use treatment agency
  • State department of health
  • Commission on Accreditation of Rehabilitation Facilities (CARF)
  • SAMHSA certification for opioid treatment program (OTP)
  • Drug Enforcement Agency (DEA)

heartbeat IconAges Served

  • Young Adults
  • Adults
PavillonFeatured Image

Pavillon

Location Pin Icon Greenville, SC 29615

Phone Icon 864-241-6688

URL address dropdown icon
http://www.pavillon.org

heartbeat IconOperating Model

  • Private non-profit organization

heartbeat IconFacility Credentials & Oversight

  • Commission on Accreditation of Rehabilitation Facilities (CARF)

heartbeat IconAges Served

  • Young Adults
  • Adults

100% Confidential and free